2014 Spring Benefit for Disorders of the Immune System

Are you healthy? How do you know?

Most of us know we are healthy by the way we feel. Typically, that same impulse lets us know if we are unhealthy.

But what if we could find out about diseases before they grow inside of us? This is the direction we are headed through ImmunoGenomics.

Immunogenomics is the application of DNA sequencing technologies and analysis of the human genome in order to understand the immune system and origins of disease.

HudsonAlpha's sixth annual Spring Benefit — Thursday, April 24 — will focus on disorders of the immune systems and ImmunoGenomics, one of biotech's most exciting and increasingly relevant fields.

2014 Double Helix Dash 5K to benefit childhood genetic disorders research

Double Helix Dash - 2013Runners, get ready for one of Huntsville's most unique races. HudsonAlpha will host the third annual Double Helix Dash 5K and 1-mile fun run on Tuesday, April 8, at 5:30 p.m.

The certified 5K course begins and ends on Genome Way in front of HudsonAlpha, winds through McMillian Park's distinctive double helix path, and extends into other points across Cummings Research Park. The 1-mile event also winds through McMillian Park.

"The support from the community for this race has been incredible," said Carter Wells, race director and vice president for advancement and economic development at HudsonAlpha. "We've had a strong turnout each of the first two years. It's a great event for individuals and families, whether they want to run, walk or simply spend an afternoon along McMillian Park. I hope everyone comes out to enjoy part of their day with us."

Pond-dwelling powerhouse’s genome points to its biofuel potential

HudsonAlpha’s Jeremy Schmutz a key contributor to milestone discovery

Duckweed is a tiny floating plant that’s been known to drive people daffy. It’s one of the smallest and fastest-growing flowering plants that often becomes a hard-to-control weed in ponds and small lakes. But it’s also been exploited to clean contaminated water and as a source to produce pharmaceuticals. Now, the genome of Greater Duckweed (Spirodela polyrhiza) has given this miniscule plant’s potential as a biofuel source a big boost. In a paper published February 19, 2014 in the journal Nature Communications, researchers from Rutgers University, the Department of Energy Joint Genome Institute, HudsonAlpha Institute for Biotechnology and several other facilities detailed the complete genome of S. polyrhiza and analyzed it in comparison to several other plants, including rice and tomatoes.

Registration opens for HudsonAlpha-Science’s 2014 Conference on ImmunoGenomics

International conference brings together preeminent leaders and thinkers at the intersection of genomics and immunology

HUNTSVILLE, Ala., Feb. 14 — Registration opens today for the HudsonAlpha-Science 2014 Conference on ImmunoGenomics, to be held Sept. 29–Oct. 1 on the HudsonAlpha biotechnology campus in Huntsville, Ala. 

The event offers a dynamic program covering the major themes of this emerging scientific field.  ImmunoGenomics sits at the heart of the movement toward ‘personalized’ medicine and the use of DNA sequencing to improve disease diagnosis and treatment.  More information, including registration and sponsorships, can be found at the event site: http://haig.aaas.org.

HudsonAlpha’s Neil Lamb testifies before House Ways and Means Education Committee on reach of science training throughout state

Montgomery, Ala. — February 12, 2014 — HudsonAlpha Vice President for Educational Outreach Neil Lamb, Ph.D., testifies today before the Alabama House of Representatives Ways and Means Education Committee about the many ways HudsonAlpha is making a difference in Alabama education.

Lamb will highlight for lawmakers how the HudsonAlpha Institute for Biotechnology is progressing in its goal to train every life science teacher across the state of Alabama on an ongoing basis.


New method developed for ranking disease-causal mutations within whole genome sequences

Approach distills vast amounts of data into a single score

Seattle, Wash. and Huntsville, Ala.—Researchers from the University of Washington and the HudsonAlpha Institute for Biotechnology have developed a new method for organizing and prioritizing genetic data. The Combined Annotation–Dependent Depletion, or CADD, method will assist scientists in their search for disease-causing mutation events in human genomes.
The new method is the subject of a paper titled “A general framework for estimating the relative pathogenicity of human genetic variants,” published in Nature Genetics.

Conversant Bio Releases Normal Bone Marrow E-Book

Published by Global Leader in Tissue and Cell Samples, Guide Offers Key Information on Normal Bone Marrow to Help Researchers

Huntsville, AL—January 28, 2014 — Conversant Bio, a global leader in supplying the highest-quality human tissue and viable cell samples, today announced it is publishing a guide to the basics of normal bone marrow and how it’s used in research. The e-book A Researcher’s Guide to Normal Bone Marrow, is available as a free download at http://www.conversantbio.com/a-researchers-guide-to-normal-bone-marrow/.

CFDRC-developed SynVivo® recognized among “Top 10 Innovations of 2013” by The Scientist

HUNTSVILLE, Ala. December 4, 2013 – CFD Research Corporation-developed SynVivo® microfluidic cell-based assay platform has been recognized as one of the "Top 10 Innovations of 2013" by The Scientist magazine. SynVivo enables faster, more efficient drug development by combining the control of in vitro testing with the realism of in vivo studies. 

Hundreds support HudsonAlpha research through R-KIDS 5K

Despite the cold, rainy weather, hundreds of runners turned out for the first R-KIDS 5K and 1-mile fun run at the Madison City Schools Stadium Saturday.

Proceeds from the event, organized by Bob Jones High School senior David Gunther, will support HudsonAlpha's pediatric genomics program. This collaborative research effort between HudsonAlpha, UAB and North Alabama Children's Specialists seeks to identify genetic causes of developmental delay in children across the Tennesee Valley.

Basic research yields knowledge of transcription factor binding sites

New, robust methodology is side benefit

HUNTSVILLE, Ala. --Whether or not a gene is expressed, that is, whether it is turned on or turned off, is in part controlled by a group of proteins called transcription factors. Scientists in the Myers lab at the HudsonAlpha Institute recently published results of a basic research project undertaken to better understand mechanisms that determine cell type-specific transcription factor binding.

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